Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. AF patients exhibit increased risks for heart attacks, heart failure, hospitalization, and death. AF is increasing in prevalence, with up to 15.1M cases estimated annually by 2050 in the USA. This increase is in large part due to aging of the […]
Therapeutics & Prevention
Despite all efforts to curb the epidemic of obesity through nutrition education, dieting, and exercise, current global efforts are failing as evidenced by the continuous rise in obesity levels, especially in developing countries. Postprandial glycemia is directly associated with the development of diabetes and obesity. Further, the intake of refined carbohydrates, e.g., made from wheat […]
Targeted and long-lasting formulations of chemotherapeutics with low doses and few side effects. Simple formulations to delivery two or more therapeutics to cancers with similar pharmacokinetic profiles. Easier to manufacture than nano / micro particles. Good to use in combination with immune checkpoint inhibitors. Clinical Applications To sensitize the responses of cancers to chemotherapeutics. rHSA-p53 […]
Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease, is a debilitating autoimmune condition that is clinically challenging to manage effectively. In the U.S., the CDC estimates that 1.3% of adults (about 3 million) have been diagnosed with IBD. Many IBD patients are diagnosed early in life. As a result of chronic […]
The microbial organism Borrelia burgdorferi causes the common infection termed Lyme disease. This infection is transferred to humans by deer ticks and is common in areas of North America and other countries where large deer populations are found. In the U.S., the CDC has estimated that up to 476,000 cases of Lyme disease were diagnosed […]