The University of the Sciences research team has uncovered CAPER as a novel therapeutic target inside breast cancer cells. CAPER has been shown to be overexpressed in these cancer cells and seems to be helping the cancer thrive and survive. Targeted cancer therapy is becoming a leading approach to cancer treatment and Dr. Jasmin and […]
Life Sciences
Human growth hormone (hGH), also known as somatotropin or somatropin, is a peptide hormone that stimulates growth and differentiation of target tissues. Exogenously administered hGH can be an effective treatment for growth disorders in both children and adults. It also is useful in treating catabolic disorders such as muscle wasting associated with acquired immunodeficiency syndrome […]
The Glucagon-Like Peptide 1 Receptor (GLP-1R), a member of Class B family of G-protein coupled receptors (GPCRs), is an effective target for the treatment of type-2 diabetes, and its incretin peptide and varied peptide mimetics are adopted drugs. Despite remarkable anti-diabetic effects, GLP-1R peptide-based agonists are limited by several disadvantages. Although considerable progress has been […]
This invention can be a useful synthetic tool for any company / laboratory that is pursuing the synthesis of benzoxaborole-containing targets. Reagents can be commercialized through a chemical supply company making them available for purchase by academic labs and / or companies. This invention currently is in laboratory use. Opportunity The Tomsho Lab has synthesized […]
Lead Inventor Clyde M. Ofner III, Ph.D Unmet Need A major challenge in cancer chemotherapy is the selective delivery of small molecule anti-cancer agents to cancer cells. Doxorubicin (DOX) is a potent antineoplastic agent that is effective against a wide range of solid tumors and lymphomas but it is also associated with an irreversible cardiomyopathy […]