Autoimmune

Anti-Bin1 Treatment of Inflammatory Bowel Disease (IBD)

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Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease, is a debilitating autoimmune condition that is clinically challenging to manage effectively. In the U.S., the CDC estimates that 1.3% of adults (about 3 million) have been diagnosed with IBD. Many IBD patients are diagnosed early in life. As a result of chronic […]

Anti-Bin1 Treatment of Alzheimer’s Disease

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Human genetics studies have identified Bin1 as second only to ApoE as a risk factor for late-onset Alzheimer’s disease (LOAD). Neurology studies indicate that Bin1 binds and influences the turnover of tau as a likely mechanism in promoting LOAD risk. Lankenau Institute for Medical Research scientists developed a cell-penetrating Bin1 antibody that appears to promote […]

Anti-IDO2 Treatment of Rheumatoid Arthritis and Autoimmune Disorders

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Rheumatoid arthritis (RA) is a chronic autoimmune disease that occurs when the body’s immune system attacks joints, creating debilitating inflammation and pain. Left unchecked this inflammatory condition can permanently damage joint structures, and in some cases, damage the cardiovascular and respiratory systems. This systemic disease affects more than 1.5 million Americans and about 1% of […]

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