Villanova University


Novel Soft Quaternary Phosphonium Compound (Soft QPC) Collection as Antimicrobial Agents

Background and Unmet Need Historically, quaternary ammonium cations (QACs) have been the standard antimicrobial agents in the current disinfectant market. However, the environmental persistence qualities of this agent are of notable concern. Long-term environmental exposure to QACs not only results in growth inhibition and lethal complications of aquatic organisms, but also contributes to antimicrobial resistance. […]

Novel Quaternary Phosphonium Compound (QPC) Disinfectants

Background and Unmet Need Quaternary ammonium compounds (QACs) are a staple disinfectant in household, agricultural, industrial, and clinical settings.  Their popularity has continued to persist due to their broad-spectrum activity against various micro-organisms. While the non-specific mechanism of QACs suggested that these compounds would evade resistance development, unfortunately, tolerance of QACs was eventually observed. Furthermore, […]

Hybrid Cooling of Battery Cells at Module Scale

Dr. Sylvie Lorente, Associate Dean for Research and Innovation, College of Engineering; Chair and Professor in Mechanical Engineering at Villanova University, has invented a novel hybrid cooling system that utilizes modular ceramic insert architecture for stationary battery storage systems.  The invention ensures batteries are separate from the coolant, while keeping the battery cells within the desired and […]

Diagnosing the Nature and Magnitude of Faults within Dynamic Systems

Complex rotating machinery is an integral part of operations across multiple industries including healthcare, medical device, robotics, and traditional manufacturing. Turbomachinery, generators, engines, pumps, servo actuators, and electrical motors all depend on intricate inner mechanisms. Rotating machinery, such as turbomachinery, generators, motors, centrifuges, aircraft engines, pumps and fans, fail often because of bearing defects.  Engines, […]

Hierarchical Structures for Isothermal Compression / Expansion for Energy Storage

In industry, compressed air is so widely used that it is often regarded as the fourth utility after electricity, natural gas, and water.  Compressed air energy storage (CAES) typically uses power from renewable energy (i.e., wind, solar) to compress air, and to generate electricity through a turbine when needed, as a way of (i) mitigating […]