Noninvasive Wearable Continuous Glucose Monitoring System

Diabetes Mellitus is increasing at an unprecedented pace; more than half a billion people are living with diabetes worldwide. The disease affects men, women, and children of all ages in every country, and that number is projected to more than double to 1.3 billion people in the next 30 years, with every country seeing an increase. The latest, most comprehensive calculations show the current global prevalence rate is 6.1%, making diabetes one of the top 10 leading causes of death and disability.

Vigilance, typically provided by monitoring devices, is important for diabetes management.  In addition to traditional glucose monitors, state-of-the-art continuous glucose monitoring devices include minimally invasive microneedle patches. However, these patches have been found to be uncomfortable and can irritate the skin. Some patients have also been found to be sensitive to the adhesive coating of the patch and some brands limit recommended use period to only 14 days. Skin irritation, common among persons with diabetes, may also be exacerbated. In addition, these devices measure glucose variations in interstitial fluids. It is well known that glucose variation in interstitial fluids is delayed from glucose variation in blood. A delay that impacts the timely management of diabetes and can be dangerous in extreme scenarios.

As result, there is a need for a product that offers the capabilities of commercially available continuous glucose monitor devices but may be more easily incorporated into the patient’s everyday life and further reduce risk of skin irritation, while providing instantaneous readings that directly correspond to the variation of glucose in blood and without any delay.

Further, because of the prevalence of diabetes, the blood glucose monitoring device market is significant, having been valued at $15.80 Bn in 2022 and expected to reach $32.99 Bn by 2030, at a CAGR of 9.9%.

Opportunity 

This experienced team has developed non-invasive biomarker monitor sensors that utilize certain electromagnetic circuits comprising of flexible and wearable antennas and microwave components to provide a completely continuous and non-invasive solution to biomarker monitoring.

The technology enables continuous measurement of biological and chemical markers, including blood glucose. This technology may be integrated into multiple, diverse garments and accessories, including jewelry.  With an accompanying mobile app, this technology will enable an easy-to-use and highly accurate biomarker monitoring system effortlessly integrated into the user’s everyday life. The computing system developed in conjunction with this technology enables very accurate, selective, and highly sensitive readings to glucose variations.

While commercially available continuous glucose monitoring devices utilize microneedle patches, this technology is a completely non-invasive method and may be tailored to be worn on multiple regions of the body. The technology’s highly scalable nature and compatibility with various areas of the body, enable its use in varied garments and accessories to offer a stylish, convenient, and concealed solution to glucose monitoring in persons with diabetes.  Further, the device is perfect for monitoring young children and infants, as it may be incorporated into everyday garments, such as socks.  Other examples include, but are not limited to, gloves, arm sleeves, necklaces, and earrings.

Because the device utilizes radio waves rather than micro needles, it eliminates the risk of skin irritation.

Finally, as this technology may be integrated into everyday garments or jewelry, it can enhance the privacy of the patient’s health status.

Unique Attributes

• Highly scalable technology to be manufactured into multiple garments or worn accessories and / or jewelry.
• Completely non-invasive platform with continuous biomarker monitoring.
• Discrete monitoring device solution to enhance user privacy.

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